<![CDATA[<?xml version="1.0"?>
<wsdl:definitions name="MOBY_Central_Generated_WSDL"
                targetNamespace="http://biomoby.org/Central.wsdl"
                xmlns:tns="http://biomoby.org/Central.wsdl"
                xmlns:xsd1="http://biomoby.org/CentralXSDs.xsd"
                xmlns:xsd="http://www.w3.org/2001/XMLSchema"
                xmlns="http://schemas.xmlsoap.org/wsdl/"
                xmlns:wsdl="http://schemas.xmlsoap.org/wsdl/"
                xmlns:wsdlsoap="http://schemas.xmlsoap.org/wsdl/soap/">

                 
  <wsdl:message name="getKolmogrovQualityControlStatisticForSlidesInNASCExperimentIdInput">
          <wsdl:part name="data" type="xsd:string"/>
  </wsdl:message>

  <wsdl:message name="getKolmogrovQualityControlStatisticForSlidesInNASCExperimentIdOutput">
          <wsdl:part name="body" type="xsd:string"/>
  </wsdl:message>

  <wsdl:portType name="getKolmogrovQualityControlStatisticForSlidesInNASCExperimentIdPortType">
          <wsdl:operation name="getKolmogrovQualityControlStatisticForSlidesInNASCExperimentId">
                 <wsdl:input message="tns:getKolmogrovQualityControlStatisticForSlidesInNASCExperimentIdInput"/>
                 <wsdl:output message="tns:getKolmogrovQualityControlStatisticForSlidesInNASCExperimentIdOutput"/>
          </wsdl:operation>
  </wsdl:portType>
                
  <wsdl:binding name="getKolmogrovQualityControlStatisticForSlidesInNASCExperimentIdBinding" type="tns:getKolmogrovQualityControlStatisticForSlidesInNASCExperimentIdPortType">
          <wsdlsoap:binding style="rpc" transport="http://schemas.xmlsoap.org/soap/http"/>
          <wsdl:operation name="getKolmogrovQualityControlStatisticForSlidesInNASCExperimentId"><!-- in essense, this is the name of the subroutine that is called -->
                 <wsdlsoap:operation soapAction='http://biomoby.org/#getKolmogrovQualityControlStatisticForSlidesInNASCExperimentId' style='rpc'/>
                 <wsdl:input>
                         <wsdlsoap:body use="encoded" namespace="http://biomoby.org/" encodingStyle="http://schemas.xmlsoap.org/soap/encoding/"/>
                 </wsdl:input>
                 <wsdl:output>
                         <wsdlsoap:body use="encoded" namespace="http://biomoby.org/" encodingStyle="http://schemas.xmlsoap.org/soap/encoding/"/>
                 </wsdl:output>
          </wsdl:operation>
  </wsdl:binding>
                
  <wsdl:service name="getKolmogrovQualityControlStatisticForSlidesInNASCExperimentIdService">
          <wsdl:documentation>Authority: ssg.uab.edu  -  Every NASC Experiment (referred by its ID or Reference Number) has a collection of microarray slides.

For expression value for each probe set across all microarrays in a group (NASC Experiment), we calculate its deleted residual by subtracting the mean expression value for that probe set across all arrays in the same group. When then calculate the studentized deleted residual by dividing the deleted residual from the first step by the probe set's standard deviation, again computed across all the arrays in the same group. We then examine all the deleted residuals from a single array. If the distribution of deleted residuals deviates significantly from a t-distribution with N-2 degrees of freedom, where N is the number of arrays in a group, then we consider it an outlier and recommend excluding it from further analyses. To identify these outlier chips, we use a Kolmogorov-Smirnov (K-S) goodness-of-fit test, which produces a test statistic (D) indicating how well the observed distribution matches the theoretical t-distribution. The D statistic ranges from 0 to 1, and larger numbers indicate greater deviation and lower quality. We recommend 0.15 as a good default cutoff, which typically removes 10-20% of the arrays.

For more information see FAQ section under, http://www.ssg.uab.edu/coexpression.

Example:

Input :
    nasc_exp_id :  57
   imageProcAlgorithm : RMA

Output:
  slides-kolmogrov_qc : simple_key_value_pair[]

Okamoto_A-1--gpa1-treated_SLD,0.19899454287139134
Okamoto_A-2-gpa1-control_SLD,0.05468188657277678
Okamoto_A-4-WT-control_SLD,0.09995232680087468</wsdl:documentation>  <!-- service description goes here -->
          <wsdl:port name="getKolmogrovQualityControlStatisticForSlidesInNASCExperimentIdPort" binding="tns:getKolmogrovQualityControlStatisticForSlidesInNASCExperimentIdBinding">
                 <wsdlsoap:address location="http://138.26.144.5:8080/axis/services/getKolmogrovQualityControlStatisticForSlidesInNASCExperimentId"/>    <!-- URL to service scriptname -->
          </wsdl:port>
  </wsdl:service>

</wsdl:definitions>


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